A postdoctoral research position in molecular modeling of metalloenzymes is available at the Department of Chemistry and Biochemistry, Concordia University, Montreal, Canada. Research will be performed under the supervision of Prof. Guillaume Lamoureux, Assistant Professor at the Department and member of the Center for Research in Molecular Modeling (CERMM).
The research will be directed towards developing new tools for computational enzymology (QM/MM, semiempirical models, bioinformatics, etc.) and -- depending on the candidate's interests -- using them to elucidate the mechanisms of enzymes such as matrix metalloproteases (linked to cancer metastasis), thermolysin-like proteins (involved in a variety of biological processes), or bacterial hemoglobins (important therapeutic targets against bacterial infections).
The project has secured funding from NSERC, and will use computing resources from the Lamoureux laboratory, the CERMM, and the RQCHP supercomputing center. It will be done in concertation with the research efforts of Prof. Darrin M. York (U. of Minnesota) on RNA catalysis.
- Ph.D. degree (or equivalent) in chemistry, physics, or a related discipline (completed or near completion)
- strong background in molecular dynamics and molecular modeling (experience with force field development, semiempirical models, or QM/MM simulations a plus)
- proven interest in biochemistry and in computational methods
To apply, please send an electronic version of your curriculum vitae and the coordinates of two referees to Prof. Lamoureux (firstname.lastname@example.org). The successful candidate will be offered a one-year contract, renewable upon satisfactory performance. The anticipated starting date is September 2009, but a later or earlier date can be arranged.
For more information, see http://faculty.concordia.ca/glamoure.