CHARMM Development Project
Posted By: ca4930 Simulated Annealing Lipid - 05/11/22 06:36 PM
I have a glycosylated protein with a GPI anchor and I'd like to perform simulated annealing to optimize the conformation of the glycans/anchor. I want to keep the protein completely fixed and in a sense mask it from the annealing process. I'm wondering if cons fix would be appropriate in this circumstance or if there is a smarter way to just optimize the positioning of the glycans?

Thanks.
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